The elderly, obese and diabetic patients would be more resistant to antidepressants

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Published the 11.01.2018 at 14h58

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dépressionpersonnes âgéesobésitérésistance

An elderly person suffering from metabolic syndrome (overweight, diabetes, HYPERTENSION, gout) would stand up more to antidepressants. These are the results of a study published in the Journal of the American Geriatrics Society.
Elderly patients with a major depressive disorder may suffer from thought disorders. The daily is more hard to manage, care also. Elderly depression also have higher risks of death.
Suffer from depression and suffering from diabetes does not good housekeeping.

The metabolic syndrome, what is it ?

The metabolic syndrome, also called syndrome X, is not truly a disease. This is a set of physiological disorders (overweight, blood glucose and blood lipids abnormal, high blood pressure, elevated uric acid), which increases the risk of type 2 diabetes, heart disease, or cerebral vascular accident (STROKE).
The metabolic syndrome is promoted by the lack of physical activity, physical inactivity, obesity and poor diet. To avoid this, it is thus necessary to adopt a healthy lifestyle.

The antidepressants are least effect

To conduct this study, the researchers have done tests on people over the age of 60, suffering from depression and metabolic syndrome.
Each participant has been treated with an antidepressant reference, venlafaxine, marketed under the name Effexor. It is indicated in the treatment and prevention of severe cases of depression, anxiety attacks and social phobia.

Strengthen the treatment

The researchers have drawn three conclusions about the persons reached of the syndrome X : their history of depression are older, the symptoms of depression are more severe at the beginning of the study, and finally, they take longer to respond to treatment.

Thus, for these researchers, older people with depression who have metabolic syndrome should be treated with a particular strategy.